H. Alex Brown is Professor of Pharmacology and Chemistry at Vanderbilt University School of Medicine. Alex grew up on the east coast of Florida close to the Kennedy Space Center. He attended Wake Forest University, received his Bachelor of Science degree with highest honors from Florida Institute of Technology and a masters degree from Syracuse University. Alex received his Ph.D. degree in 1992 from the University of North Carolina at Chapel Hill working in the laboratory of T. Kendall Harden and then pursued postdoctoral training in the Department of Pharmacology at the University of Texas-Southwestern Medical Center with Paul Sternweis. Alex joined the faculty at Cornell University in 1996 with appointments in Pharmacology and Biochemistry Molecular & Cell Biology. Alex received the Sidney Kimmel Foundation for Cancer Research Scholar award in 1997. Working with Fred McLafferty at Cornell, Alex developed the field of computational lipidomics in his laboratory utilizing electrospray ionization mass spectrometry. Al Gilman, then the director of the Alliance for Cellular Signaling (AfCS), invited Alex to use this emerging technology to contribute to the AfCS research program. In 2002, Alex was recruited to Vanderbilt University School of Medicine as the Ingram Professor of Cancer Research in Pharmacology. Alex has been the director of the glycerophospholipid core for the LIPID Metabolites and Pathways Strategy (LIPID MAPS) consortium since 2003. He has served on the editorial board for the Journal of Biological Chemistry, NIH-NIGMS & NIHLB study section, ASBMB publications committee, and as associate editor of Molecular Pharmacology from 2006 until 2009. In addition, Alex was editor of a three volume series on Lipidomics and Bioactive Lipids for Methods in Enzymology, co-editor with Lawrence Marnett of a thematic issue on lipid biochemistry for Chemical Reviews in 2011, and has organized multiple international conferences on lipid metabolism & signaling. Alex received the Vanderbilt Ingram Cancer Center (VICC) “High Impact Publications Award” in 2010, as well as the Vanderbilt University Medical Center “Leadership of a Multi-Investigator Team Award” together with Craig Lindsley in 2011. Alex is currently Metabolomics co-director for the Scripps-Vanderbilt Human Chemical Sciences Institute and the associate director of System Analysis for the Vanderbilt Institute of Chemical Biology (VICB). His current research is focused on understanding the roles of lipid molecular species and phospholipases in cellular functions and human disease.